(function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){ (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) })(window,document,'script','//www.google-analytics.com/analytics.js','ga'); ga('create', 'UA-22375394-1', 'auto'); ga('send', 'pageview');


Bill & Melinda Gates Foundation

Bill and Melinda Gates Foundation (BMGF) is the largest nonprofit fighting poverty, disease, and inequity around the world. Founded on a simple premise: that people everywhere, regardless of identity or circumstances, should have the chance to live healthy, productive lives. By building a global and cultural workplace that supports greater diversity, equity, and inclusion — of voices, ideas, and approaches — together with their employees and partners, they can help all people improve their lives from poverty and health to education. As an organization, they offer full healthcare premiums coverage, generous paid time off, contribution to your retirement fund, several employee communities, and a commitment to embedding diversity, equity, and inclusion into everything they do.

Role purpose

The Global Health Program (GHP) harnesses advances in science and technology to save lives in poor countries. This program focuses on the health problems that have a major impact in developing countries but get too little attention and funding. Where proven tools exist, BMGF supports sustainable ways to improve delivery. Where tools don’t exist, BMGF invests in research and development of new interventions, such as vaccines, drugs, biologics, and diagnostics. We focus our strategies to fight and prevent HIV/AIDS, malaria, tuberculosis, neglected tropical diseases, enteric and diarrheal diseases, and pneumonia. Their maternal, neonatal and child health program focuses on ensuring that women and newborns survive and remain healthy before, during and after childbirth, and ensuring optimal growth, neurodevelopment and resistance to disease, by identifying and addressing underlying biological vulnerabilities. BMGF also supports innovative research in reproductive health. These strategies are supported by functional teams that focus on Discovery & Translational Sciences, Vaccine Development & Surveillance (VD&S), and Integrated Development.


The Vaccine Development Team advances public goods for global health through technological innovation. We do this by accelerating the development and commercialization of novel vaccines and the sustainable manufacture of existing vaccines, defining the global disease burden through better primary data and world-class modeling, and reducing the threat of epidemics.


Duties and Responsibilities

The Senior Program Officer (SPO), Clinical, is accountable for implementing and managing grants and contracts to build sound clinical and integrated vaccine development plans, as well as provide technical support to various vaccine programs supported across the foundation. These include programs in novel polio vaccines, RSV, pneumonia, malaria, enteric diseases, and HPV. This person will provide crucial project management, grant management, and communication plans on Vaccine Development priorities and to internal Program Strategy Teams (PSTs), Product Development Partners (PDPs) and other foundation partners. He/she will also partner with leaders in key functional areas to contribute to the team’s strategic vision including participating in the setting of the overall strategy and goals for the group.  The Vaccine Development Team also progresses cross-cutting vaccine initiatives exploring correlates of protection, combination vaccines and vaccine schedules which are otherwise not addressed within a single strategy team.


This person will be a key member of the Vaccine Development Clinical Domain and report to the Deputy Director of Clinical Development.


What the SPO will do:

  • Negotiate, implement, and run a portfolio of grants or performance-based contracts, including alignment of partners, review of letters of inquiry and grant proposals as well as providing clear, concise, and insightful written analyses and recommendations for funding.
  • Apply strategic and technical/scientific expertise to lead integrated clinical development plans for vaccine development in support of rapid response vaccine platforms and the acceleration of vaccine development coupled with improvement vaccine coverage supporting diseases with epidemic/pandemic potential.
  • Partner closely with team leadership, including the Director, DD Integrated Clinical Vaccines Development, DD CMC Vaccine Development and DD Vaccine Regulatory, to communicate and implement the overall Vaccine Development strategy.
  • Consult, provide thought partnership, and support to grantees to increase the impact of projects and the creation of well-integrated vaccine development plans, clinical study designs, statistical analysis plans, and clinical assays for vaccine clinical studies.
  • Serve as an advisor on clinical vaccine study design leveraging immune correlates where appropriate, including the review of protocols, analysis plans, and clinical sections of regulatory dossiers.
  • Development strategy on cross-cutting foundation efforts to advance appropriate combination vaccines and optimized vaccine schedules to enable improved impact against vaccine preventable diseases.
  • Work closely with the Discovery and Translational Sciences (D&TS) team on pre-clinical and early clinical pipeline to support and ensure smooth transitions of vaccines into full clinical development.
  • Provide technical mentorship and support on the foundation process for Integrated Product Development Plans (IPDPs) and the development process including definition of critical milestones and stage gates. Support product development process as defined by the foundation.
  • Support the evaluation of new vaccine technologies, providing input on potential clinical development pathway.
  • Manage information related to grant portfolio and domain-level data, such as documenting key activities and decisions; inputting into key business processes and performance measurement tools; preparing materials for communication with foundation leadership.
  • Forge collaborations with key global experts in vaccine development and work with external advisors to advance innovative approaches to vaccine development.
  • Represent foundation interests in developing networks for the program.
  • This role will require the ability to travel up to 30% domestically and internationally.


Education, Qualifications & Experience

The ideal candidate is someone who enjoys the opportunity of working on complex projects and collaboratively crafting solutions that have the potential for transformational change. We seek a self-starter who can integrate a diverse set of perspectives to build consensus, structure, and drive progress, and provide technical and operational capacity to the VD&S portfolio. You have the following experience:

  • MD and/or PhD with proven experience in one or more of the following areas: clinical research & development, vaccine development, infectious diseases and/or immunology.
  • Experience in working with different vaccine platforms and/or experience working on product development plans.
  • Extensive knowledge of clinical vaccine research from phase 1 through phase 4 including statistical capabilities.
  • Demonstrated ability to learn new disease areas and new vaccine technologies quickly.
  • Ability to lead and affect evidence-based strategy planning and implementation process.
  • Demonstrated excellence in scientific writing and data analysis, written and oral communication skills, and experience advocating and communicating with a broad and diverse audience.
  • Demonstrated ability to work with flexibility, efficiency, and passion in a fast-paced environment.
  • Proven program and stakeholder management skills: ability to coordinate inputs from many people; to track progress against targets and identify barriers to progress; to plan agendas and facilitate meetings; and to organize, evaluate, and communicate information.
  • Strong judgment skills and abilities to handle issues, multiple tasks, confidential information, and opposing priorities with skill, discretion, a strong attention to detail, flexibility, and diplomacy.


Other Attributes

  • Experience working with developing country vaccine manufacturers a plus.
  • Tolerance for ambiguity and ability to apply structure to simplify problems.
  • Exceptional listening, verbal, and written communication skills, able to effectively calibrate input and synthesize information to connect with diverse audiences.
  • Demonstrated passion for the Foundation’s values with a commitment to deliver results against our mission.


Role Location

The role can be performed remotely within the USA with a strong preference for Seattle, WA. Candidates living in London, UK will also be considered.


Relocation and visa support is provided for candidates to relocate to the USA or London.  


How to Apply

If you wish to be considered for this position please complete the Application Form below on or before 3 February 2023. In addition, we encourage you to please attach a copy of the most recent English version of your CV.


All information will be treated in the strictest confidence.


If you have an initial query rather than an application, kindly email us at BMGF-SPOVCD@sri-executive.com


 SRI Executive is exclusively retained by Bill and Melinda Gates Foundation to undertake this assignment.


Application form

Personal Details
Work Experience
Attach Resume
Required Field
Any Additional Documentation (Optional)