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About

TB Alliance

For a high-quality overview of the role along with more information on TB Alliance, please click on this link.

 

The TB Alliance is preeminent in the TB drug Research & Development and Market Access space, pursuing faster, simpler treatments for all forms of TB through bridging the expertise and functionality of the pharmaceutical industry with public health interests to meet a major unmet global health need.

 

TB Alliance is a product development partnership (PDP) with a successful track record accelerating the development and adoption of urgently needed new anti-tuberculosis (TB) drugs. With an annual operating budget of approximately $100 million, including ~$45M in negotiated indirect funding, TB Alliance leads the advancement of the most comprehensive portfolio of TB drug candidates in history.

 

Currently, a portfolio of more than twenty projects spanning screening through Phase III clinical development to access and adoption is being advanced. TB Alliance successes include delivering new drug regimens to patients, including securing stringent regulatory authority approval, commercialization in concert with pharmaceutical partners, country adoption of new regimens, and widespread availability. The transformative BPaL/M regimens have been approved by regulatory agencies in 28 countries and available in more than 150 countries worldwide.

 

TB Alliance is the only not-for-profit drug developer to develop a new chemical entity (NCE) for tuberculosis treatment from discovery through to patients and is a recipient of the Prix Galien award for the USA FDA approval of pretomanid. Lastly, the TB Alliance leverages its drug discovery and development capabilities as well as its’ scientific assets in adjacent disease areas, where unmet needs exist, such as leprosy, Buruli ulcer, as well as mycobacterium avium and abscessus.

 

TB Alliance deploys a unique not-for-profit operating model characterized by a small core of highly experienced internal staff, primarily from the biotechnology and pharmaceutical industry, with capabilities extending across the drug development value chain from discovery research, through to achieving widespread access to improved TB drugs. Based in New York City, the TB Alliance has a global footprint, with staff positioned strategically in a variety of countries, now including South Africa, India, Ukraine, Brazil, Singapore and Switzerland.

 

For more information, visit www.tballiance.org.

Role purpose

The primary goal of the Senior Vice President of External Affairs (SVP EA) is to lead, strategically and operationally, a broad, multi-faceted resource generation program to enable the TB Alliance to achieve its long-term goals, building on the present excellent relationships with current donors, identifying and evaluating novel opportunities while working closely with other senior leaders to establish and facilitate external relationships, and oversee execution of organizational goals to achieve desired results.

 

The SVP EA is also responsible for establishing the TB Alliance’s external positioning and advancing its reputation, through strategic communications with funders/prospective funders, media, and all other constituencies, building engagement with stakeholders, advocating for supportive public policies, and ensuring strategic and operational leadership.

 

This individual will be knowledgeable about a wide range of funding sources globally, across the public and private sector. They will be well-versed in the public health policymaking process and will conceptualize and implement plans to influence decision-making and advocacy in support of resource mobilization.

 

The ideal candidate must have or develop a broad understanding of the organization's activities in discovery, development, and delivery of improved treatments for tuberculosis and adjacent disease areas. They must be able to effectively optimize both traditional and novel resource generation channels, including but not limited to:

 

  • Public sector sources, including but not confined to:
    • Development agencies such as the Foreign, Commonwealth and Development Office (UK), Department of Foreign Affairs and Trade (Australia), Global Affairs Canada (GAC), Global Health, Security & Diplomacy/US State Department (US).
    • Scientific/medical research agencies such as the Chinese Academy of Medicine, the US National Institute of Health (NIH), and the Indian Council of Medical Research (India).
    • Health ministries in target countries.
  • Private sources of relevant funding such as foundations e.g. Gates Foundation and Wellcome Trust.
  • Public-private partnerships such as Innovative Health Initiative (IHI).
  • Multi-lateral organizations such as UNITAID and the European and Developing Countries Clinical Trial Partnership (EDCTP).
  • Resource and infrastructure sharing partnerships, such as the ACTG (Advancing Clinical Therapeutics Globally), and other leveraged or in-kind contributions.
  • Corporate and individual philanthropic sources.

 

The ideal candidate will have had experience across many of the above channels with the ability to quickly develop mastery within each. In addition, she or he must have significant leadership expertise, ability to establish effective relationships internally and externally, and marshal resources across the organization as well as directly manage an effective team.

 

Major Duties and Responsibilities

Oversee resource generation, grant management and funder relationships.

  • Define and quantify the organization’s short- and long-term funding needs in collaboration with other senior leaders.
  • Develop TB Alliance resource generation plans, with emphasis on long term sustainability, and ensure the plans reflect a balanced and diverse set of sources, including direct income e.g. grants, and indirect sources of funding such through leveraging and resource sharing initiatives.
  • Identify and develop relationships with networks and multi-party consortia to increase funding and influence, such as public-private initiatives, clinical trial consortia and/or product introduction networks e.g. Innovative Health Initiative (IHI).
  • In concert with other leaders, identify innovative financing mechanisms and structures for new bilateral and multi-party relationships to financially support development and introduction of new TB drug regimens.
  • Oversee management of existing donor relationships, including reporting and grant compliance.
  • Oversee proposal development including strategizing, writing, and submission.

 

Influence public health policy and generate political and financial commitments for TB drug regimen development and product introduction, through advocacy, communications, and stakeholder engagement.

  • Raise awareness about the need for R&D for new TB drug regimens among national and international policymakers, donors, the research/scientific community and the public health community.
  • Engage governments and multilaterals to allocate greater funding and implement policies to facilitate TB drug R&D.
  • Increase political commitment for new TB drug regimen development by influencing key multilateral and bilateral policy statements, declarations and actions.
  • Apply policy research to build the evidence base for public policy.
  • Develop and promote partnerships and convene/participate in coalitions with other product development partnerships (PDP) to support advocacy strategies. Apply policy research to build the evidence base for funding and identify financial, scientific, and political barriers to product development and introduction of new TB drug regimens for adults and children, and generate policy recommendations to address them.
  • Advise on strategies to communicate and influence thinking and planning around such issues.

 

Establish TB Alliance external positioning, advance stakeholder engagement, and advance TB Alliance’s reputation in support of long-term goals.

  • Define and execute strategic communications programs including a robust publication strategy, targeted regional communications, and other tactics designed to advance TB Alliance’s reputation and support the achievement of specific goals.
  • Develop and execute a comprehensive stakeholder engagement strategy, at global and regional or local levels, in support of achieving short- and long-term goals.

 

Profile

Overall, the SVP EA will ideally have the following skills and experience:

  • Track record of prior success with resource generation across a broad array of channels, ideally using scientific advancement and public health underpinnings as the platform for financial support, and relevant policy changes. Track record of securing financial and policy support for innovation, scientific advancements, global health, and related areas.
  • Creative thinking and embodying an entrepreneurial approach to a complex and multi-faceted environment is essential.
  • Strong business acumen and experience, ideally including working knowledge of drug product research and development, product introduction and uptake.
  • Outstanding communication and influencing skills with the ability to effectively present TB Alliance messages, both orally and in writing, to relevant constituencies both internally and externally, including the media, partner organizations and prospective donors.
  • A willingness to work at both a strategic and tactical level, with oversight responsibility and hands-on operational involvement.
  • Flexibility and good prioritization skills to produce high quality, accurate outputs under pressure and tight deadlines.
  • Well-honed judgment and analytical skills.
  • Strong organizational and administrative skills.
  • An energetic, positive attitude and determination to succeed.
  • A systematic and methodical approach, embracing change and growth.
  • Substantial track record of successful resource development, ideally in global health, scientific research, or pharmaceutical product development and adoption (15+ years).
  • Working knowledge of national and health policy environments and familiarity with the current funding environment for drug R&D in TB, and other neglected diseases is ideal, along with familiarity with the tuberculosis treatment landscape for both adults and children.
  • At a personal level, we are seeking a leader who possesses strong decision-making capabilities, communications skills, flexibility, adaptability and is innovative and entrepreneurial. This individual will also contribute materially to the overall TB Alliance strategy and direction. Commitment to the mission of the TB Alliance and the broader global health mission is essential.

 

The SVP EA will report to and work directly with the Chief Executive Officer, in addition to working closely with the heads of other TB Alliance departments and with the Board of Directors.

 

Terms of Appointment

As part of our overall compensation package, we offer a competitive salary, comprehensive health benefits, generous retirement contributions, and work/life flexibility designed to support the employee and immediate family.

 

Starting salary is expected to be in the range of $300,000 – $385,000, exact salary will be commensurate with skills and experience.

 

TB Alliance is an Equal Employment Opportunity employer. This job description should not be construed to imply that these requirements are the only standards for the position. Other duties may be assigned.

 

TB Alliance has the right to revise this job description at any time. TB Alliance is an “at will” employer and as such, neither this job description nor your signature constitutes any form of contractual arrangement between you and TB Alliance.

 

Role Location

Position is based in New York City, NY (US), with the incumbent ideally located within commutable distance. A flexible, hybrid schedule is available. Domestic and international travel will be required, up to 25%.

 

Other relevant locations may be considered. Relocation assistance and support for securing US work authorization is available.

 

How to Apply

To apply for this position, please ensure you complete the Application Form provided below by 12 September 2025 (23:59 hrs, GMT -4). It is essential that you submit your CV in English, specifically in Microsoft Word format (.doc/.docx), not exceeding 10MB.

 

Applications in other languages or formats will not be considered.

 

Rest assured, all information will be handled with the utmost confidentiality.

 

SRI Executive is exclusively retained by TB Alliance to undertake this assignment.

 

Application form

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